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Lakers vs. Timberwolves Prediction: Game 4 Odds & Expert Picks, April 26
Pictured: Los Angeles Lakers forward LeBron James looks on against the Minnesota Timberwolves. Photo by Jesse Johnson via Imagn Images.

Roughly 39 hours after closing out Game 3, Minnesota aims to take a 3-1 series lead over Los Angeles, and our Lakers vs. Timberwolves prediction backs a decisive blow from the home team.

Expecting the Lakers to regroup on such a short turnaround feels like a tall task, which is why the Timberwolves are 3.5-point favorites. Tipoff for Game 4 is set for 3:30 p.m. ET (ABC) on Sunday at Target Center in Minneapolis, and our NBA picks expect the Timberwolves to take a commanding lead in this series.

💰 Lakers vs. Timberwolves expert picks for Game 4

🔎 Our NEW NBA player prop odds tool can help you find the best NBA odds across legal sportsbooks in your area!

✅ Against the spread pick: Timberwolves -3 (-112 via DraftKings) ⭐⭐⭐⭐
✅ Moneyline pick: Timberwolves ML (-155 via DraftKings) ⭐⭐⭐⭐⭐
✅ Over/Under pick: Under 209.5 (-110 via Caesars) ⭐⭐⭐

🏀 Game 4 prediction & best bet

🎯 Score prediction: Timberwolves 105, Lakers 95

Friday’s game was so important to the Lakers because the turnaround to Game 4 favors a young Timberwolves team. It’s difficult to imagine LeBron James bouncing back after scoring 38 points in 41 minutes. Luka Doncic doesn’t have much time to get over his illness.

I recommend the Timberwolves’ moneyline as my best bet, but there are many ways to bet on them effectively finishing this series on Sunday. 

For one, Minnesota has been a second-half team in this matchup, besting Los Angeles in the second half of all seven head-to-head meetings this year. During the regular season, Minnesota ranked No. 2 in the league with a second-half net rating of plus-7.8. Los Angeles was 25th at minus-4.7.

As of this writing, there aren’t second-half lines available, but if Los Angeles starts in front, it could create a good live opportunity. Caesars offers +460 odds for the Lakers to win the first half and the Timberwolves to win the second half.

I don’t expect the Lakers to have the stamina on Sunday.

✅ Best bet: Timberwolves ML (-155 via DraftKings)

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📈 Lakers vs. Timberwolves odds

Live updated odds from our best sports betting sites.

🪧 Game 4 opening odds

Opening odds via BetMGM.

  • Spread: Lakers +3.5 (-115) | Timberwolves -3.5 (-105)
  • Moneyline: Lakers +135 | Timberwolves -161
  • Over/Under: Over 209.5 (-110) | Under 209.5 (-110)

🚑 Lakers vs. Timberwolves injury report

Follow the official NBA injury report for more injury news.

📡 How to watch Lakers vs. Timberwolves live (Game 4)

📅 Sunday, April 27
🕗 3:30 p.m. ET
📍 Target Center (Minneapolis)
📺 ABC | 🛜 ESPN+

💵 Best NBA betting sites

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